Researchers have developed eco-friendly silver nanoparticles from Magnolia alba leaf extract. These nanoparticles present enhanced antioxidant and dye-degrading properties with potential medical and environmental functions.
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Plant-Based mostly Various to Chemical Strategies
Silver nanoparticles are valued for his or her antimicrobial, antioxidant, and anticancer results, however typical manufacturing strategies usually use hazardous chemical compounds and require massive volumes of vitality.
Plant-based silver nanoparticles, utilizing plant extracts wealthy in pure compounds similar to phenols and flavonoids, current a safer, extra sustainable, and cost-effective different. These phytochemicals act as each lowering and capping brokers, facilitating the formation of steady nanoparticles whereas avoiding poisonous by-products.
Totally different plant extracts affect the scale, form, and organic exercise of the nanoparticles produced. Magnolia alba, recognized for its numerous phytochemicals, has by no means been examined for nanoparticle synthesis till now.
Synthesis
Described in Scientific Studiesthe researchers collected Magnolia alba leaves, processing them to supply an aqueous leaf extract (MLE).
Phytochemical screening confirmed the extract’s variety; MLE contained secondary metabolites together with carbohydrates, proteins, saponins, steroids, tannins, and terpenoids.
The crew used a inexperienced artificial technique to supply the silver nanoparticles, mixing an aqueous silver nitrate (AgNO3) answer with MLE below managed situations. The silver ions (Ag+) have been diminished to metallic silver (Ag0), leading to a visual color change within the answer from pale to darkish brown.
Characterisation utilizing scanning electron microscopy (SEM) confirmed the nanoparticles have been spherical, with an approximate measurement of 40 nm, an optimum vary for mobile uptake in biomedical functions. The nanoparticles remained steady for at the very least six months when saved at 4 °C.
Antioxidant Exercise Enhanced
The researchers assessed the antioxidant potential of the nanoparticles by measuring complete flavonoid content material (TFC) and complete phenolic content material (TPC).
TFC was decided utilizing an aluminium chloride colourimetric technique, which measures the flexibility of flavonoids to type complexes with aluminium ions, detectable at 415 nm. TPC was quantified with the Folin-Ciocalteu reagent, which reacts with phenolic compounds to supply a blue chromogen, detected at 765 nm.
Each TFC and TPC have been considerably greater within the nanoparticle formulations than within the leaf extract. These findings point out that the surface-bound flavonoid and phenolic compounds enhanced the free radical scavenging capabilities of the nanoparticles.
This may very well be significantly precious in functions geared toward mitigating oxidative stress, together with most cancers remedy, wound therapeutic, and drug supply.
Photocatalytic Potential for Water Remedy
Photocatalytic degradation research demonstrated the potential of the nanoparticles in environmental cleanup. They efficiently decolorized methyl orange dye in water, which the researchers used to simulate wastewater contamination.
Within the experiment, the nanoparticles have been combined with a methyl orange answer and sodium borohydride (NaBH4) as a lowering agent. The crew measured the dye’s absorbance at common intervals to trace its degradation.
Outcomes confirmed environment friendly dye breakdown below gentle situations, which was attributed to the big floor space and reactive floor websites of the MLE silver nanoparticles, demonstrating their potential for environmental remediation.
What’s Subsequent?
The research offered the formation of steady, spherical silver nanoparticles, roughly 40 nm in measurement, utilizing a inexperienced, eco-friendly technique and Magnolia alba leaf extract.
The nanoparticles displayed enhanced antioxidant capacities, seemingly as a result of phytochemicals retained on their floor, and demonstrated vital photocatalytic exercise in dye degradation exams.
To evaluate the biocompatibility and cytotoxicity of those nanoparticles, additional research are beneficial, in addition to exams to judge their efficiency in sensible, real-world eventualities. Such work might assist set up Magnolia alba-derived silver nanoparticles as a secure and efficient choice for each medical and environmental functions.
Journal Reference
De Mel S., et al. (2025). Inexperienced synthesis of silver nanoparticles utilizing Magnolia alba leaf extracts and evaluating their antimicrobial, anticancer, antioxidant, and photocatalytic properties. Scientific Studies 15, 23709. DOI: 10.1038/s41598-025-08468-3, https://www.nature.com/articles/s41598-025-08468-3.
